Orangeburg County Development Commision

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Workforce & Education

Strategic Location

Located in the heart of Central South Carolina, the region offers direct access to I-26, I-95, and key freight corridors connecting major Southeast markets. With close proximity to the Port of Charleston, a well-established industrial base, and ample room for expansion, the area is built to support growth. A business-ready environment, backed by strong local and state partnerships, ensures companies can scale efficiently and competitively.

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By the Numbers

Orangeburg County demonstrates the scale, connectivity, and workforce capacity that support sustained industrial growth. From its geographic reach and multimodal transportation network to a manufacturing-led economy and a deep regional labor pool, the data reflects a location built for performance and expansion.

2nd

Largest County in South Carolina by Land Mass

5

Strategic Interstates

2

Mainline Rail Carriers - CSX and Norfolk Southern

Why Orangeburg?

A strategic choice comes down to fundamentals. A strong manufacturing base, access to higher education institutions, competitive utility rates with reliable capacity, and a consistently business-friendly environment create the conditions companies need to operate efficiently and grow with confidence.

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1.2 Million

Workforce Draw within a 60-Minute Drive Time.

Business Friendly

Competitive Utility Rates & Strong Present & Future Capacity

3 Higher Educational Institutions

#1

Sector in Orangeburg County is Manufacturing

Featured Parks & Sites

SC Gateway Logistics Park

320 Inca Court, Vance, SC, 29142

Location: Vance, South Carolina

Size: 1,275 Acres

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Orangeburg County Power Site

Location: Hwy 21 near Prosperity Drive, Orangeburg, SC, 29115

Size: 745± acres

Carolina International Commerce Park

Location: I-26 & Industrial Bvld., Orangeburg, SC, 29118

Size: 93± acres

Tri-County Global Industrial Site

Location: 4100 St Matthews Rd, Orangeburg, SC, 29118

Size: 380± acres

John W. Matthews, Jr. Industrial Park

Location: Highway 301 and Logistics Drive, Cameron, SC, 29018

Size: 542± acres

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Target Business Sectors

Orangeburg County supports industries that build, move, grow, and innovate at scale. From aerospace and automotive manufacturing to advanced manufacturing, agribusiness, and life sciences, our target sectors reflect where performance, workforce capability, and infrastructure align. These industries aren’t emerging here—they’re established, supported, and positioned for long-term growth. Explore how Orangeburg County delivers the sites, talent, and operational readiness companies need to compete.